Royal Air Force Typhoon fighter aircraft have conducted a mission with France's air force in a joint strike against an hidden munitions depot in Syria operated by the IS group, as stated by the British defence ministry.
The location, located using reconnaissance, was believed to be housing weapons and explosive materials, the statement said, and was located in hills just to the north of Palmyra in central Syria.
"Our fighter planes utilized precision-guided Paveway IV munitions to hit a series of access tunnels leading to the facility... initial indications suggest the target was engaged successfully," the ministry announced.
There was no sign of any harm to civilians in the attack on Saturday evening and each participating jet returned to base without incident, the MoD added.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
IS - referred to as Daesh - imposed jihadist rule over significant areas in Iraq and Syria until 2019.
"This operation shows the UK's leading role, and commitment to operate in unison with allied nations, to eradicate any re-emergence of the terrorist group and their dangerous and violent ideologies in the Middle East," Britain's Defence Chief the minister remarked.
UK warplanes have carried out overwatch operations over Syria to "forestall any attempted comeback" of Islamic State following its military defeat at the Baghuz confrontation in the year 2019, the authorities noted.
"I must thank the personnel of the UK armed forces involved in this mission for their skill and their bravery," Healey commented. "They were among a great many UK service members deployed over Christmas and New Year. This mission, to take out dangerous terrorists who endanger our way of life, shows how our armed forces are always on standby, continuously, ensuring Britain's security within its borders and strong abroad."
Last December, the American forces conducted what it termed a "major assault" on IS targets in Syria, after an ambush claimed the lives of two US servicemembers and a civilian linguist in Palmyra.
The United Nations estimates Islamic State still boasts an estimated 5,000 to 7,000 combatants in Iraq and Syria.